I rebuilt my engine a couple of years ago after 80k hard miles (and undetected detonation). I used a recommended local engine builder, who charged me $3500 including parts (forged pistons, roller cam 206/206, valve springs, seals, locks and seats, pushrods, bearings, timing set, lifters, oil pump, water pump). The engine runs stronger and smoother than ever. I now use a Scanmaster to prevent detonation. I will probably rebuild the transmission this spring, since I am getting a little slippage between gears at low throttle.
One challenge to rebuilding the engine is to find a builder who is experienced with this engine. I think parts in general will become more available as time goes by as F-bodies become more and more collectable.